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Big Pharma Gets CRISPRed

34cunningham From Scientific American: Money from Genes: CRISPR Goes Commercial The new DNA-changing tech has attracted millions of dollars from AstraZeneca, DuPont and other big companies

. nike roshe flyknit hombre . Justin Pugh Chaussures ASICS Gel Glorify pour Femme . nike air jordan 11 femme Bryan Stork Colin Kaepernick Jersey borsello adidas uomo prezzo It was only a matter of time before the technique moved beyond academia, and in 2015 a number of companies have invested in Crispr technology. New Balance 446 homme asics gel lyte 5 hombre blancas asics gel pulse 8 m?skie First it was pharma heavyweight Novartis, which signed two separate deals with gene-editing start-ups Intellia Therapeutics and Caribou Biosciences. Canotte NBA a Poco Prezzo Cooper Bateman Jersey

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  • It plans to use Crispr for engineering immune cells and blood stem cells, and as a research tool for drug discovery. nike tn requin

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    In Salvo 34 (Fall 2015), our resident bio-ethicist Paige Cunningham gave us a brief report on what CRISPR is, how it’s being advanced, and the ethical dilemmas surrounding it. new balance 373 uomo prezzo FLYKNIT LUNAR3

    nike air max 2017 goedkoop Excerpted briefly below:

    “This should not be done. Fjallraven Kanken Sale Classic I am not alone.”1 This was bioethicist Ruth Macklin’s reaction to an announcement made earlier this year by a team of Chinese scientists to the effect that they had “edited” the DNA of human embryos in an effort to correct a genetic mutation that can cause thalassemia, a serious blood disease. louboutin soldes To edit the DNA, the team used CRISPR/Cas9, an enzyme complex. Nike Air Max 1 Homme sac à dos fjallraven kanken pas cher When injected into a cell, CRISPR/Cas9 acts like micro-scissors. buy albion gold

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  • It targets the defective section of DNA, snips it out, and replaces it with healthy DNA provided by the researcher.

  • The technique is well established for editing adult human cells—for instance, to modify a patient’s bone marrow cells to increase resistance to HIV—and has also been used on animals. Nike Air Max 95 Femme Adidas Zx 700 soldes It is so common in genetics research, in fact, that it has become a verb, as in “I’m going to CRISPR that.”2 When it is functioning correctly, CRISPR/Cas9 identifies all mutated segments and repairs each one with a corrected DNA segment. Nike Air Foamposite Pro Every cell in the research specimen should be changed. Asics Hombre That is not what happened in the Chinese study.

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    Genetic engineering can be divided into two streams: (1) genetic modifications that are performed on adult human cells, called somatic cell therapy, affecting only the patient, and (2) germline modifications that are inheritable, that is, passed along to subsequent generations. Adidas Zx 500 Og Femme Philadelphia 76ers

    Adidas Goedkoop Madison Bumgarner Authentic Jersey In the case of somatic cell therapy, ethical concerns center on the customary issues of informed consent, safety, efficacy, and so forth.

    Salvo Links

    Some articles of interest from around the web: The Atlantic What America Lost as Women Entered the Workforce Civic organizations were built on the voluntary labor of women. ffxiv gil cheap Adidas Zx Flux Femme Leopard Denver Nuggets Nike Air Jordan 6
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  • communities are suffering. The Guardian A world without work is coming – it could be utopia or it could be hell Robots will eventually do all our jobs,

    SPLC: The Self-Appointed, National Thought-Crime Hall Monitor

    The Poverty Palace

    The Poverty Palace

    From the New York Times:

    For the second time, George W. Nike Air Max 90 Femme Air Max 90 Bianco Donna

    Bush has written a warm letter in support of a conservative group that bills itself as promoting the “natural family” based on heterosexual marriage but that is classified as a hate group by the Southern Poverty Law Center. The group, the World Congress of Families, based in Rockford, Ill., is holding a conference in Tbilisi, Georgia, where it had planned to honor Mr. asics gel nimbus 15 femme Bush. Asics 2017 Goedkoop new balance 993 denmark But he declined to attend, a spokesman said. nike air max pas cher Nike Air Max 2017 Heren zwart In a letter dated May 2016, the former president says: “I commend your efforts to recognize the importance of families in building nations. Your work improves many lives and makes the world better.”

    The article continues:

    The Southern Poverty Law Center, which tracks hate groups, added the World Congress of Families to its list in 2014, calling it “one of the key driving forces behind the U.S.

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  • religious right’s global export of homophobia and sexism.” But the liberal-leaning center has been criticized for including groups that fall within the conservative mainstream, like the Family Research Council, based on their stances on gay issues. nike air max pas cher Chaussures ASICS Gel Glorify pour Femme The World Congress of Families has strongly disputed the hate-group designation and the implication that it supports violence against the L.G.B.T. community. “Nothing could be further from the truth, as W.C.F. Asics Gel Kinsei 6 Femme strongly opposes violence and would never advocate violence or hatred toward any group of people, regardless of differences,” the group wrote in 2014. nike air zoom pegasus 32 uomo Larry Jacobs, the group’s managing director, said in a statement that it seeks to fight “the sexual revolution and the harm that it has brought millions of victims worldwide.”

    We here at Salvo support The World Congress of Families and the work of The Howard Center, one of the groups responsible for putting it together (and also a Salvo partner organization). New Balance 373 m?skie The Southern Poverty Law Center has been targeted in Salvo‘s “Surveillance” column. asics scarpe tennis bambino I encourage you to read up on the SPLC, I’ve posted an excerpt from the Salvo article below. adidas yeezy boost 350 v2 m?skie Nike Air Max 95 m?skie Frankly, I’d be proud to be on their naughty list.

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    . Asics Gel Kinsei 6 Homme nike air jordan 11 mujer With the KKK having, thankfully, shriveled to a statistically trivial 2,000 members by the year 2000, the SPLC moved away from filing lawsuits to raising awareness about the threat of “hate groups.” A cursory look at the organizations so designated, though, reveals a malignant streak.

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  • Organizations that uphold pro-life, pro-family, and pro-marriage (of the man-woman variety) morals are (ta-da!) “hate groups” and earn a spot on the SPLC’s “Hate Map.” (Yes, Salvo would qualify.) Like a self-appointed, national thought-crime hall monitor, the SPLC presents regular “intelligence files” and an annual “Year in Hate” report to municipal, state, and federal law enforcement agencies. New Balance 247 m?skie Never mind that traditional morality does not constitute “hate,” and that “heightened awareness” by itself has never helped the actual victims of anything, “hate-mapping,” too, is apparently quite profitable. According to tax records, at the end of 2010 the SPLC was sitting on “private investment funds” exceeding $200 million, with Dees and top SPLC execs—including co-founder Levin—collecting annual salaries well into six figures. Adidas ZX Flux Heren They have stamped out poverty quite splendidly—for themselves. There’s big money in hate.

    Further reading from Salvo: • Family Matters An Interview with Allan Carlson, President of the Howard Center by Bernard Chapin • World War Sex A Global Revolution Imperils Men, Women & Children: An Interview with Gabriele Kuby by Benjamin J. Chaussures adidas Vail And up at the Touchstone blog: The Dangerous Foolishness of Modern Man by Michael Avramovich

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    Throwing fuel on the fire, Professor Marci Hamilton of the University of Pennsylvania, believes that the Religious Freedom Restoration Act (RFRA), passed in 1993 and signed by President Bill Clinton, gives a green light to discriminate today. chaussures de foot new balance RFRA bans the federal government from unjustly meddling in the way Americans express religious beliefs. Adidas Zx Flux Homme Nike Air Max 2016 Dames Roze RFRA provides “a claim or defense to persons whose religious exercise is substantially burdened by government.” But that is not exactly how Professor Hamilton sees things. New Balance 247 homme C.J. Wilson Jersey In a recent interview with CBS, available here, Professor Hamilton said that RFRA is “Jim Crow. It’s just that there are different targets at this point for some of the people. Nike Air Max [Religious traditionalists and conservatives] are arguing now, in these groups, is that they have ‘rights’ in order to be able to discriminate against others. nike air max 2016 dames But the ‘rights’ that they’re talking about are made up. They are not rights from the Constitution.” Thus, according to Professor Hamilton, religious liberty, although cited as our first freedom in the First Amendment, is not constitutional, whereas unlimited abortion license, a redefinition of marriage, and now, transgender bathroom policies throughout the nation, which are not in the Constitution, are fundamental constitutional rights. adidas bounce uomo . Nike Air Max 98 Homme .

    Douglass, the Play

    An interesting review of a play about Frederick Douglass from The Weekly Standard:

    “Douglass” a Timely Play amid Modern Racial Strife Thomas Klingestein’s Frederick Douglass is optimistic, conservative—and occupied with personal disputes. sac lancel pas cher Timeliness is a virtue, and Thomas Klingenstein’s Douglass, which had its world-premiere this past summer at the Theater Wit in Chicago, captures the zeitgeist of our period of increasing racial tension. Nike Cortez enfants Through Douglass, Klingenstein hopes to reinvigorate our contemporary debates by revisiting the life and struggles of its titular character. Nike Air Max 2017 Dames Canotte Indiana Pacers Goedkope Nike Air Max 1 Douglass is presented as a story of redemption. asics pas cher nike air max 1 print mujer At its founding the United States was burdened by the original sin of slavery, which needed to be expunged before it undermined the motivating principles of the Declaration and Constitution. Nike Air Max 1 Femme

    Adidas Pas Cher Some men—such as the abolitionist William Lloyd Garrison and black nationalist Martin Delany—believe the damage has been done. Nike Zoom All Court CK Nike Hurley Phantom Free mochilas kanken baratas The American dream is beyond salvation, as the sin of slavery had poisoned the tree of liberty down to its very roots. Nike Air Max 2016 Italia

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  • Contrasted with these radical perspectives—one radically left, the other radically right—is the moderating wisdom of Frederick Douglass. corrida asics golden run 2016 He begins the play as an acolyte of Garrison, and struggles with the appeal of the intransigent positions of both Garrison and Delany. Nike Air Max BW

  • There is something attractive in radicalism, particularly for the dispossessed. New Balance 1300 femme Nike Air Huarache Donna It is sound and fury; a cathartic release, but one Douglass comes to realize is incapable of meaningful political action. adidas superstar 2 homme Kirk Cousins Redskins Jerseys . . Parajumpers Femme Lavelle Hawkins Nike Air Max 2016 Heren Goedkoop Adidas Stan Smith . nike air max flyknit uomo Soldes Fjallraven Kanken Tennis Nike France nike air max 2016 goedkoop soldes adidas chaussures sport nautique homme Read the rest.

    I also recommend this article on Frederick Douglass from the Salvo archives: Sabbath School On the Emancipation of Frederick Douglass by Means of Liberal Education by Thomas Jodziewicz

    True wisdom has suggested that the only way to find one’s real self is, paradoxically, to get out of oneself, “to be beside oneself,” as philosopher Josef Pieper phrased it.

    Our popular culture promotes the injurious fiction that the world is all about me, myself, and my ephemeral needs, a temptation that American culture has confronted for a long time. Fjallraven Kanken No.2 But a true liberal arts education can provide an escape from such alienation and loneliness—and boredom. New Balance 990 femme A true liberal education is a way to discover that you are not alone.

    As we share great texts and ideas and works of art, our vision and expectations can be enlarged. soldes chaussures nike nike air max 1 goedkoop nike air max 2017 pas cher Air Max 2017 Dames zwart New Balance 1600 damskie It does take work, and a peculiar type of courage to admit that there’s a world larger than the self while fear is all about us, but we are meant to be citizens of that larger world. sac a dos fjallraven kanken femme The study of the liberal arts—the kind of study that means examination and not just memorization—can be a foundation or grounding for one’s work, one’s vocation, and really for one’s life in a larger world than oneself.

    Take Frederick Douglass, for example. nike air max thea print prezzo Douglass (1818—1895) escaped from slavery in Maryland in 1838. sac fjallraven kanken Seven years later he published the Narrative of the Life of Frederick Douglass, An American Slave, Written by Himself, the first of several autobiographies. . Nike Air Max Thea Femme Grise Nike Air Max Dames Goedkoop Air Foamposite One . .

    Enduring the Movies

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    Which means he’s gonna get beat up soon.” width=”150″ height=”150″ /> Max expressing his concerns (mansplaining). Nike Air Max 2011 Homme Ryan Kerrigan Redskins Jerseys Nike Air Foamposite Pro Max will get beat up by a girl soon.

    Recently I’ve been digging through the archives on the Salvo website looking for articles to recirculate (The website is updated daily so check back often!). nike air max 2017 heren nike italy milano Well, one of the gems that I found was Girly Men: The Media’s Attack on Masculinity by S. Mac Jones Jersey T. AIR ZOOM PEGASUS 34

    Canotte Portland Trail Blazers Karnick. Chaussures adidas Air Jordan 5 Retro asics pas cher It’s from 2008 so some of the pop culture examples he gives are a bit dated, but the thesis of the article still holds up. In fact, we’re simply further down the road on that issue. Marqise Lee – USC Trojans adidas gazelle Nike Air Max 2017 Dames blauw So it was with this article in the back of my mind that I stumbled upon Propaganda Pop Culture: From Cuckmercials to ‘Star Wars’ at the Taki’s Magazine website. nike air max 1 femme beige Air Max Baratas Solde adidas superstar The author Gavin McInnes not only points out the current P.C. craziness, but he offers helpful ways to go to the movies and get out unscathed by the SJW propaganda, and in some cases even with a renewed faith in humanity! Here’s what I mean. New Balance 574 Donna

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    When watching a female Jedi reboot the Star Wars franchise and solve all the universe’s problems you simply say, “Of course this woman is extraordinary. Kyrie Irving All Shoes New Balance 993 m?skie That’s why she’s going to save the universe. Jordan 1 enfants nike pas chers You wouldn’t have some random slob taking down the First Order.” When you see the black guy babble like a toddler, you forgive his lack of personality. asics kayano 21 donna “He just left the stormtroopers,” you say to yourself. fjallraven kanken large 20 L “He’s a fish out of water. Of course he’s acting like a ridiculous baby.” At the end of the film (another spoiler) we meet Luke Skywalker. Kopen nike air max schoenen “Well, they all basically worship him,” you tell yourself. nike tn homme blanche

  • “In that sense they’re respecting all the hard work white men have done in the past. asics gel kinsei 4 femme Adidas ZX Flux Heren He’s Jesus in a way. sklep new balance 966 meskie It’s a Christian film.” To enjoy any kind of pop culture these days, you inject your suspension of disbelief with steroids and comb through hundreds of metaphors looking for something that even sort of resembles a plausible reality. ADIDAS VALCLEAN2 CMF

    nike air max 2015 donnagoedkoop nike air max 2017 It works for Mad Max, too. Nike Air Jordan femme Sure, Max himself is in the background and it’s all about Charlize Theron, but look at the precious cargo they’re carrying: pregnant women. new balance 1980 zante roma Charlize’s character is as childless as she is miserable. nike air force 1 mid hombre The pregnant women in this movie are depicted as the future of the world. Air Jordan Eclipse Homme Asics Whiz?er damskie Maglia David Robinson In that sense, it’s a pro-life movie that venerates moms—stay-at-home moms, no less. New Balance 1400 hombre nike air max 2017 pas cher Nike Air Max Sko All right, I like it now. Nike Air Max Command Femmes

    Let’s grab some popcorn.

    Good stuff.